Mississippi River Cruises

United States River Cruises

Sail in beautifully appointed ship along the country’s celebrated waterways

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Recommended Sailings

Featured Mississippi River Viking Cruises

  • Viking Mississippi
    4.1 rating out of 5  (14 reviews)

    7 Night Mississippi Delta Explorer

    Viking Mississippi

    Departing from: New Orleans, Louisiana
    Ports of Call:
    • Darrow, Louisiana
    • St. Francisville, Louisiana
    • Natchez, Mississippi
    • Vicksburg, Mississippi
    • River Cruising
    • Memphis, Tennessee
    Sailing Dates:
    • October 2025
    • November 2025
    • February 2026
    • March 2026
    • April 2026
    • May 2026
    • September 2026
    • October 2026
    • December 2026
    • January 2027
    • February 2027
    • March 2027
    • April 2027
    • May 2027
    • June 2027
    • September 2027
    • November 2027
    interior from
    Not Available
    oceanview from
    $4,299
    $614pernight
    balcony from
    $4,299
    $614pernight
    suite from
    $4,999
    $714pernight
    Rewards & Bonus Offers:
    • Exclusive: Up to $400 Instant Savings
    • Limited Time: $25 Deposits
    • Spring Sale: Reduced Cruise Fares
    • Bonus Offer: $500 to Spend on Board
    • Includes - Shore Excursion in every port of call, free Wi-Fi, more
    • Exclusive: Up to $1,000 to Spend on Board
     
    Riverview from $4,299
    ($614pernight)
    4.1 rating out of 5  (14 reviews)
  • Viking Mississippi
    4.1 rating out of 5  (14 reviews)

    7 Night Mississippi Delta Explorer

    Viking Mississippi

    Departing from: Memphis, Tennessee
    Ports of Call:
    • Greenville, Mississippi
    • Vicksburg, Mississippi
    • Natchez, Mississippi
    • St. Francisville, Louisiana
    • Baton Rouge, Louisiana
    • Darrow, Louisiana
    • New Orleans, Louisiana
    Sailing Dates:
    • November 2025
    • December 2025
    • February 2026
    • March 2026
    • April 2026
    • May 2026
    • June 2026
    • September 2026
    • October 2026
    • November 2026
    • December 2026
    • February 2027
    • March 2027
    • April 2027
    • May 2027
    • June 2027
    • November 2027
    interior from
    Not Available
    oceanview from
    $4,299
    $614pernight
    balcony from
    $4,199
    $600pernight
    suite from
    $4,999
    $714pernight
    Rewards & Bonus Offers:
    • Exclusive: Up to $400 Instant Savings
    • Limited Time: $25 Deposits
    • Spring Sale: Reduced Cruise Fares
    • Bonus Offer: $500 to Spend on Board
    • Includes - Shore Excursion in every port of call, free Wi-Fi, more
    • Exclusive: Up to $1,000 to Spend on Board
     
    Balcony from $4,199
    ($600pernight)
    4.1 rating out of 5  (14 reviews)
  • Viking Mississippi
    4.1 rating out of 5  (14 reviews)

    14 Night Americas Great River

    Viking Mississippi

    Departing from: St. Paul, Minnesota
    Ports of Call:
    • Red Wing (Minneapolis), Minnesota
    • La Crosse, Wisconsin
    • Dubuque, Iowa
    • Quad Cities, Iowa
    • Burlington, Iowa
    • Hannibal, Missouri
    • St. Louis, Missouri
    • Scenic Cruising - Sail The Lower Mississippi
    • Memphis, Tennessee
    • Greenville, Mississippi
    • Vicksburg, Mississippi
    • Natchez, Mississippi
    • Baton Rouge, Louisiana
    • New Orleans, Louisiana
    Sailing Dates:
    • July 2025
    • September 2025
    • October 2025
    interior from
    Not Available
    oceanview from
    $13,999
    $1,000pernight
    balcony from
    $12,299
    $879pernight
    suite from
    $17,999
    $1,286pernight
    Rewards & Bonus Offers:
    • Exclusive: Up to $400 Instant Savings
    • Limited Time: $25 Deposits
    • Spring Sale: Reduced Cruise Fares
    • Includes - Shore Excursion in every port of call, free Wi-Fi, more
    • Exclusive: Up to $1,000 to Spend on Board
    • Call for the Best Value
     
    Balcony from $12,299
    ($879pernight)
    4.1 rating out of 5  (14 reviews)

More United States River Cruises

  • Viking Mississippi
    4.1 rating out of 5  (14 reviews)

    7 Night New Orleans & Southern Charm

    Viking Mississippi

    Departing from: New Orleans, Louisiana
    Ports of Call:
    • Darrow, Louisiana
    • St. Francisville, Louisiana
    • Natchez, Mississippi
    • Vicksburg, Mississippi
    • Baton Rouge, Louisiana
    Sailing Dates:
    • November 2025
    • December 2025
    • January 2026
    • December 2026
    • January 2027
    • June 2027
    • December 2027
    interior from
    Not Available
    oceanview from
    $3,499
    $500pernight
    balcony from
    $3,749
    $536pernight
    suite from
    $4,999
    $714pernight
    Rewards & Bonus Offers:
    • Exclusive: Up to $400 Instant Savings
    • Limited Time: $25 Deposits
    • Spring Sale: Reduced Cruise Fares
    • Bonus Offer: $500 to Spend on Board
    • Includes - Shore Excursion in every port of call, free Wi-Fi, more
    • Exclusive: Up to $1,000 to Spend on Board
     
    Riverview from $3,499
    ($500pernight)
    4.1 rating out of 5  (14 reviews)
  • American Independence
    4.6 rating out of 5  (8 reviews)

    7 Night Historic South & Golden Isles

    American Independence

    Departing from: Charleston, South Carolina
    Ports of Call:
    • Beaufort, South Carolina
    • Hilton Head Island, South Carolina
    • Savannah, Georgia
    • Jekyll Island, Georgia
    • Amelia Island, Florida
    • Jacksonville, Florida
    Sailing Dates:
    • April 2026
    interior from
    Not Available
    oceanview from
    $4,610
    $659pernight
    balcony from
    $5,490
    $784pernight
    suite from
    $6,065
    $866pernight
    Rewards & Bonus Offers:
    • Up to $2,000 Visa Prepaid Card
    • Complimentary Dining, Cocktail Parties and More
     
    Riverview from $4,610
    ($659pernight)
    4.6 rating out of 5  (8 reviews)
  • American West
    5 rating out of 5  (1 reviews)

    7 Night Columbia & Snake Rivers

    American West

    Departing from: Clarkston, Washington
    Ports of Call:
    • Cruise Snake River, Pacific Northwest, Usa
    • Pendleton, Oregon
    • The Dalles, Oregon
    • Cruise Columbia River, Pacific Northwest, Usa
    • Mount St. Helens, Washington
    • Astoria, Oregon
    • Portland, Oregon
    Sailing Dates:
    • May 2025
    • June 2025
    • July 2025
    • August 2025
    • September 2025
    • October 2025
    interior from
    Not Available
    oceanview from
    $5,240
    $749pernight
    balcony from
    $6,240
    $891pernight
    suite from
    $8,290
    $1,184pernight
    Rewards & Bonus Offers:
    • Up to $2,000 Visa Prepaid Card
    • Complimentary Dining, Cocktail Parties and More
     
    Riverview from $5,240
    ($749pernight)
    5 rating out of 5  (1 reviews)
  • American West
    5 rating out of 5  (1 reviews)

    7 Night Columbia & Snake Rivers

    American West

    Departing from: Portland, Oregon
    Ports of Call:
    • Hayden Island, Portland, Oregon
    • Astoria, Oregon
    • Mount St. Helens, Washington
    • Cruise Columbia River, Pacific Northwest, Usa
    • The Dalles, Oregon
    • Pendleton, Oregon
    • Cruise Snake River, Pacific Northwest, Usa
    • Clarkston, Washington
    Sailing Dates:
    • May 2025
    • June 2025
    • July 2025
    • August 2025
    • September 2025
    • October 2025
    interior from
    Not Available
    oceanview from
    $5,240
    $749pernight
    balcony from
    $6,240
    $891pernight
    suite from
    $8,290
    $1,184pernight
    Rewards & Bonus Offers:
    • Up to $2,000 Visa Prepaid Card
    • Complimentary Dining, Cocktail Parties and More
     
    Riverview from $5,240
    ($749pernight)
    5 rating out of 5  (1 reviews)
  • American Splendor
    4.1 rating out of 5  (4 reviews)

    7 Night Lower Mississippi River

    American Splendor

    Departing from: New Orleans, Louisiana
    Ports of Call:
    • Oak Alley Plantation, Vacherie, Louisiana
    • Houmas House Plantation, Louisiana
    • St. Francisville, Louisiana
    • Natchez, Mississippi
    • Vicksburg, Mississippi
    • Cleveland, Mississippi
    • Memphis, Tennessee
    Sailing Dates:
    • May 2025
    • June 2025
    • July 2025
    • November 2025
    • February 2026
    • March 2026
    • April 2026
    • May 2026
    • June 2026
    interior from
    Not Available
    oceanview from
    $4,295
    $614pernight
    balcony from
    $4,915
    $702pernight
    suite from
    $6,800
    $971pernight
    Rewards & Bonus Offers:
    • Up to $2,000 Visa Prepaid Card
    • Complimentary Dining, Cocktail Parties and More
     
    Riverview from $4,295
    ($614pernight)
    4.1 rating out of 5  (4 reviews)
  • American Splendor
    4.1 rating out of 5  (4 reviews)

    7 Night Tennessee Rivers

    American Splendor

    Departing from: Nashville, Tennessee
    Ports of Call:
    • Clarksville, Tennessee
    • Paducah, Kentucky
    • Savannah, Tennessee
    • Florence, Alabama
    • Decatur, Alabama
    • Chattanooga, Tennessee
    Sailing Dates:
    • July 2025
    • August 2025
    interior from
    Not Available
    oceanview from
    $3,545
    $506pernight
    balcony from
    $4,165
    $595pernight
    suite from
    $6,050
    $864pernight
    Rewards & Bonus Offers:
    • Up to $2,000 Visa Prepaid Card
    • Complimentary Dining, Cocktail Parties and More
     
    Was $4,915 – Save up to 15%
    Riverview from $3,545
    ($506pernight)
    4.1 rating out of 5  (4 reviews)
  • American Splendor
    4.1 rating out of 5  (4 reviews)

    7 Night Music Cities

    American Splendor

    Departing from: Nashville, Tennessee
    Ports of Call:
    • Clarksville, Tennessee
    • Dover, Tennessee
    • River Cruising
    • Paducah, Kentucky
    • River Cruising
    • Memphis, Tennessee
    Sailing Dates:
    • June 2025
    • July 2025
    • September 2025
    • October 2025
    interior from
    Not Available
    oceanview from
    $3,860
    $551pernight
    balcony from
    $4,525
    $646pernight
    suite from
    $6,500
    $929pernight
    Rewards & Bonus Offers:
    • Up to $2,000 Visa Prepaid Card
    • Complimentary Dining, Cocktail Parties and More
     
    Was $5,275 – Save up to 14%
    Riverview from $3,860
    ($551pernight)
    4.1 rating out of 5  (4 reviews)
  • American Independence
    4.6 rating out of 5  (8 reviews)

    7 Night Chesapeake Bay

    American Independence

    Departing from: Baltimore, Maryland
    Ports of Call:
    • Yorktown, Virginia
    • Crisfield, Maryland
    • Cambridge, Maryland
    • St. Michaels, Maryland
    • Annapolis, Maryland
    Sailing Dates:
    • May 2025
    • April 2026
    • May 2026
    • June 2026
    • July 2026
    • August 2026
    • September 2026
    • October 2026
    • May 2027
    • June 2027
    • July 2027
    • August 2027
    • September 2027
    • October 2027
    interior from
    Not Available
    oceanview from
    $4,610
    $659pernight
    balcony from
    $5,490
    $784pernight
    suite from
    $6,065
    $866pernight
    Rewards & Bonus Offers:
    • Up to $2,000 Visa Prepaid Card
    • Complimentary Dining, Cocktail Parties and More
     
    Riverview from $4,610
    ($659pernight)
    4.6 rating out of 5  (8 reviews)
  • American Star
    4.5 rating out of 5  (9 reviews)

    7 Night New England Islands

    American Star

    Departing from: Providence, Rhode Island
    Ports of Call:
    • New Bedford, Massachusetts
    • Nantucket, Massachusetts
    • Martha's Vineyard, Massachusetts
    • Block Island, Rhode Island
    • Newport, Rhode Island
    • Bristol, Rhode Island
    Sailing Dates:
    • May 2025
    • June 2025
    • July 2025
    • August 2025
    • September 2025
    interior from
    Not Available
    oceanview from
    $4,740
    $677pernight
    balcony from
    $5,740
    $820pernight
    suite from
    $7,790
    $1,113pernight
    Rewards & Bonus Offers:
    • Up to $2,000 Visa Prepaid Card
    • Complimentary Dining, Cocktail Parties and More
     
    Was $6,240 – Save up to 8%
    Riverview from $4,740
    ($677pernight)
    4.5 rating out of 5  (9 reviews)
  • American Spirit
    4.7 rating out of 5  (11 reviews)

    7 Night Puget Sound & San Juan Islands

    American Spirit

    Departing from: Seattle, Washington
    Ports of Call:
    • Anacortes, Washington
    • Friday Harbor, San Juan Island, Washington
    • Cruise San Juan Islands
    • Victoria, British Columbia
    • Port Townsend, Washington
    • Poulsbo, Washington
    Sailing Dates:
    • May 2025
    • June 2025
    • July 2025
    • August 2025
    • September 2025
    • May 2026
    • June 2026
    • July 2026
    • August 2026
    • September 2026
    interior from
    Not Available
    oceanview from
    $5,255
    $751pernight
    balcony from
    $6,315
    $902pernight
    suite from
    $8,485
    $1,212pernight
    Rewards & Bonus Offers:
    • Up to $2,000 Visa Prepaid Card
    • Complimentary Dining, Cocktail Parties and More
     
    Was $6,615 – Save up to 5%
    Riverview from $5,255
    ($751pernight)
    4.7 rating out of 5  (11 reviews)

Mississippi River Cruises

Our luxury cruise experts assist with every aspect of booking Mississippi river cruises, including getting you the most value on your luxury cruise vacation. Sail away on the world’s most luxurious cruise lines including Viking River Cruises and American Queen Cruises. Our concierge services include airport transfers, shore excursions and dining/spa reservations on all luxury Mississippi river cruises. We cater to customers who value exceptional service, product knowledge, and first-hand experience above all else. Receive complimentary onboard perks and unparalleled service when you book luxury Mississippi river cruises.

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