American Cruise Lines
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Recommended Sailings

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  • American Splendor
    4.1 rating out of 5  (4 reviews)

    7 Night Tennessee Rivers

    American Splendor

    Departing from: Chattanooga, Tennessee
    Ports of Call:
    • Decatur, Alabama
    • Florence, Alabama
    • Savannah, Tennessee
    • Paducah, Kentucky
    • Clarksville, Tennessee
    • Nashville, Tennessee
    Sailing Dates:
    • August 2025
    interior from
    Not Available
    oceanview from
    $4,295
    $614pernight
    balcony from
    $4,915
    $702pernight
    suite from
    $6,800
    $971pernight
    Rewards & Bonus Offers:
    • Up to $2,000 Visa Prepaid Card
    • Complimentary Dining, Cocktail Parties and More
     
    Riverview from $4,295
    ($614pernight)
    4.1 rating out of 5  (4 reviews)

American Cruise Lines

  • American Splendor
    4.1 rating out of 5  (4 reviews)

    7 Night Lower Mississippi River

    American Splendor

    Departing from: New Orleans, Louisiana
    Ports of Call:
    • Oak Alley Plantation, Vacherie, Louisiana
    • Houmas House Plantation, Louisiana
    • St. Francisville, Louisiana
    • Natchez, Mississippi
    • Vicksburg, Mississippi
    • Cleveland, Mississippi
    • Memphis, Tennessee
    Sailing Dates:
    • May 2025
    • June 2025
    • July 2025
    • November 2025
    • February 2026
    • March 2026
    • April 2026
    • May 2026
    • June 2026
    interior from
    Not Available
    oceanview from
    $4,295
    $614pernight
    balcony from
    $4,915
    $702pernight
    suite from
    $6,800
    $971pernight
    Rewards & Bonus Offers:
    • Up to $2,000 Visa Prepaid Card
    • Complimentary Dining, Cocktail Parties and More
     
    Riverview from $4,295
    ($614pernight)
    4.1 rating out of 5  (4 reviews)
  • American Splendor
    4.1 rating out of 5  (4 reviews)

    7 Night Music Cities

    American Splendor

    Departing from: Nashville, Tennessee
    Ports of Call:
    • Clarksville, Tennessee
    • Dover, Tennessee
    • River Cruising
    • Paducah, Kentucky
    • River Cruising
    • Memphis, Tennessee
    Sailing Dates:
    • June 2025
    • July 2025
    • September 2025
    • October 2025
    interior from
    Not Available
    oceanview from
    $3,860
    $551pernight
    balcony from
    $4,525
    $646pernight
    suite from
    $6,500
    $929pernight
    Rewards & Bonus Offers:
    • Up to $2,000 Visa Prepaid Card
    • Complimentary Dining, Cocktail Parties and More
     
    Was $5,275 – Save up to 14%
    Riverview from $3,860
    ($551pernight)
    4.1 rating out of 5  (4 reviews)
  • American Splendor
    4.1 rating out of 5  (4 reviews)

    7 Night The Tennessee Rivers

    American Splendor

    Departing from: Chattanooga, Tennessee
    Ports of Call:
    • Decatur, Alabama
    • Florence, Alabama
    • Savannah, Tennessee
    • Paducah, Kentucky
    • River Cruising
    • Nashville, Tennessee
    Sailing Dates:
    • August 2026
    • September 2026
    interior from
    Not Available
    oceanview from
    $4,295
    $614pernight
    balcony from
    $4,915
    $702pernight
    suite from
    $6,800
    $971pernight
    Rewards & Bonus Offers:
    • Up to $2,000 Visa Prepaid Card
    • Complimentary Dining, Cocktail Parties and More
     
    Riverview from $4,295
    ($614pernight)
    4.1 rating out of 5  (4 reviews)
  • American Independence
    4.6 rating out of 5  (8 reviews)

    7 Night Chesapeake Bay

    American Independence

    Departing from: Baltimore, Maryland
    Ports of Call:
    • Yorktown, Virginia
    • Crisfield, Maryland
    • Cambridge, Maryland
    • St. Michaels, Maryland
    • Annapolis, Maryland
    Sailing Dates:
    • May 2025
    • April 2026
    • May 2026
    • June 2026
    • July 2026
    • August 2026
    • September 2026
    • October 2026
    • May 2027
    • June 2027
    • July 2027
    • August 2027
    • September 2027
    • October 2027
    interior from
    Not Available
    oceanview from
    $4,610
    $659pernight
    balcony from
    $5,490
    $784pernight
    suite from
    $6,065
    $866pernight
    Rewards & Bonus Offers:
    • Up to $2,000 Visa Prepaid Card
    • Complimentary Dining, Cocktail Parties and More
     
    Riverview from $4,610
    ($659pernight)
    4.6 rating out of 5  (8 reviews)
  • American Constellation
    4.9 rating out of 5  (7 reviews)

    7 Night Puget Sound & San Juan Islands

    American Constellation

    Departing from: Seattle, Washington
    Ports of Call:
    • Anacortes, Washington
    • Friday Harbor, San Juan Island, Washington
    • Cruise San Juan Islands
    • Victoria, British Columbia
    • Port Townsend, Washington
    • Poulsbo, Washington
    Sailing Dates:
    • May 2025
    • September 2025
    • October 2025
    interior from
    Not Available
    oceanview from
    $4,675
    $668pernight
    balcony from
    $5,490
    $784pernight
    suite from
    $7,540
    $1,077pernight
    Rewards & Bonus Offers:
    • Up to $2,000 Visa Prepaid Card
    • Complimentary Dining, Cocktail Parties and More
     
    Was $6,240 – Save up to 12%
    Riverview from $4,675
    ($668pernight)
    4.9 rating out of 5  (7 reviews)
  • American Constitution
    5 rating out of 5  (4 reviews)

    7 Night Puget Sound & San Juan Islands

    American Constitution

    Departing from: Seattle, Washington
    Ports of Call:
    • Anacortes, Washington
    • Friday Harbor, San Juan Island, Washington
    • Victoria, British Columbia
    • Port Townsend, Washington
    • Poulsbo, Washington
    Sailing Dates:
    • May 2025
    • September 2025
    • October 2025
    • March 2026
    • April 2026
    • May 2026
    • September 2026
    • October 2026
    interior from
    Not Available
    oceanview from
    $5,100
    $729pernight
    balcony from
    $5,865
    $838pernight
    suite from
    $7,795
    $1,114pernight
    Rewards & Bonus Offers:
    • Up to $2,000 Visa Prepaid Card
    • Complimentary Dining, Cocktail Parties and More
     
    Riverview from $5,100
    ($729pernight)
    5 rating out of 5  (4 reviews)
  • American Symphony
    3.5 rating out of 5  (5 reviews)

    7 Night Lower Mississippi River

    American Symphony

    Departing from: New Orleans, Louisiana
    Ports of Call:
    • Oak Alley Plantation, Vacherie, Louisiana
    • Houmas House Plantation, Louisiana
    • St. Francisville, Louisiana
    • Natchez, Mississippi
    • Vicksburg, Mississippi
    • Cleveland, Mississippi
    • Memphis, Tennessee
    Sailing Dates:
    • July 2025
    • September 2025
    • April 2026
    • July 2026
    • September 2026
    • November 2026
    • December 2026
    interior from
    Not Available
    oceanview from
    Not Available
    balcony from
    $4,165
    $595pernight
    suite from
    $6,050
    $864pernight
    Rewards & Bonus Offers:
    • Up to $2,000 Visa Prepaid Card
    • Complimentary Dining, Cocktail Parties and More
     
    Was $4,915 – Save up to 15%
    Balcony from $4,165
    ($595pernight)
    3.5 rating out of 5  (5 reviews)
  • American Symphony
    3.5 rating out of 5  (5 reviews)

    7 Night Lower Mississippi River

    American Symphony

    Departing from: Memphis, Tennessee
    Ports of Call:
    • Cleveland, Mississippi
    • Vicksburg, Mississippi
    • Natchez, Mississippi
    • St. Francisville, Louisiana
    • River Cruising
    • Oak Alley Plantation, Vacherie, Louisiana
    • Houmas House Plantation, Louisiana
    • New Orleans, Louisiana
    Sailing Dates:
    • July 2025
    • August 2025
    • November 2025
    • April 2026
    • July 2026
    • August 2026
    • November 2026
    • December 2026
    interior from
    Not Available
    oceanview from
    Not Available
    balcony from
    $4,165
    $595pernight
    suite from
    $6,050
    $864pernight
    Rewards & Bonus Offers:
    • Up to $2,000 Visa Prepaid Card
    • Complimentary Dining, Cocktail Parties and More
     
    Was $4,915 – Save up to 15%
    Balcony from $4,165
    ($595pernight)
    3.5 rating out of 5  (5 reviews)
  • American Pride
    4.4 rating out of 5  (7 reviews)

    7 Night Columbia & Snake Rivers

    American Pride

    Departing from: Portland, Oregon
    Ports of Call:
    • Hayden Island, Portland, Oregon
    • Astoria, Oregon
    • Mount St. Helens, Washington
    • Cruise Columbia River, Pacific Northwest, Usa
    • The Dalles, Oregon
    • Pendleton, Oregon
    • Cruise Snake River, Pacific Northwest, Usa
    • Clarkston, Washington
    Sailing Dates:
    • May 2025
    • June 2025
    • July 2025
    • August 2025
    • September 2025
    • October 2025
    interior from
    Not Available
    oceanview from
    $5,255
    $751pernight
    balcony from
    $6,055
    $865pernight
    suite from
    $8,485
    $1,212pernight
    Rewards & Bonus Offers:
    • Up to $2,000 Visa Prepaid Card
    • Complimentary Dining, Cocktail Parties and More
     
    Was $6,355 – Save up to 5%
    Riverview from $5,255
    ($751pernight)
    4.4 rating out of 5  (7 reviews)
  • American Melody
    5 rating out of 5  (8 reviews)

    7 Night Lower Mississippi River

    American Melody

    Departing from: Memphis, Tennessee
    Ports of Call:
    • Cleveland, Mississippi
    • Vicksburg, Mississippi
    • Natchez, Mississippi
    • St. Francisville, Louisiana
    • River Cruising
    • Oak Alley Plantation, Vacherie, Louisiana
    • Houmas House Plantation, Louisiana
    • New Orleans, Louisiana
    Sailing Dates:
    • May 2025
    • November 2025
    • December 2025
    • April 2026
    • May 2026
    • November 2026
    interior from
    Not Available
    oceanview from
    Not Available
    balcony from
    $4,775
    $682pernight
    suite from
    $6,795
    $971pernight
    Rewards & Bonus Offers:
    • Up to $2,000 Visa Prepaid Card
    • Complimentary Dining, Cocktail Parties and More
     
    Was $5,275 – Save up to 9%
    Balcony from $4,775
    ($682pernight)
    5 rating out of 5  (8 reviews)
  • American Harmony
    5 rating out of 5  (6 reviews)

    7 Night Columbia & Snake Rivers

    American Harmony

    Departing from: Portland, Oregon
    Ports of Call:
    • Hayden Island, Portland, Oregon
    • Astoria, Oregon
    • Mount St. Helens, Washington
    • Cruise Columbia River, Pacific Northwest, Usa
    • The Dalles, Oregon
    • Pendleton, Oregon
    • Cruise Snake River, Pacific Northwest, Usa
    • Clarkston, Washington
    Sailing Dates:
    • May 2025
    • June 2025
    • July 2025
    • August 2025
    • September 2025
    • October 2025
    • March 2026
    • April 2026
    • May 2026
    • June 2026
    • July 2026
    • August 2026
    • September 2026
    • October 2026
    interior from
    Not Available
    oceanview from
    Not Available
    balcony from
    $6,215
    $888pernight
    suite from
    $8,785
    $1,255pernight
    Rewards & Bonus Offers:
    • Up to $2,000 Visa Prepaid Card
    • Complimentary Dining, Cocktail Parties and More
     
    Was $6,715 – Save up to 7%
    Balcony from $6,215
    ($888pernight)
    5 rating out of 5  (6 reviews)
  • American Constellation
    4.9 rating out of 5  (7 reviews)

    7 Night Southeast Alaska

    American Constellation

    Departing from: Juneau, Alaska
    Ports of Call:
    • Haines, Alaska
    • Glacier Bay National Park, Alaska (Scenic Cruising)
    • Petersburg, Alaska
    • Cruise Wrangell Narrows, Alaska
    • Wrangell, Alaska
    • Cruise Tracy Arm Fjord, Alaska
    Sailing Dates:
    • May 2025
    • June 2025
    • July 2025
    • August 2025
    • September 2025
    • May 2026
    • June 2026
    • July 2026
    • August 2026
    • September 2026
    interior from
    Not Available
    oceanview from
    $6,125
    $875pernight
    balcony from
    $7,140
    $1,020pernight
    suite from
    $9,680
    $1,383pernight
    Rewards & Bonus Offers:
    • Up to $2,000 Visa Prepaid Card
    • Complimentary Dining, Cocktail Parties and More
     
    Was $7,740 – Save up to 8%
    Riverview from $6,125
    ($875pernight)
    4.9 rating out of 5  (7 reviews)
  • American Constellation
    4.9 rating out of 5  (7 reviews)

    10 Night Alaskan Explorer

    American Constellation

    Departing from: Juneau, Alaska
    Ports of Call:
    • Haines, Alaska
    • Cruise Inside Passage, Alaska
    • Glacier Bay National Park, Alaska (Scenic Cruising)
    • Sitka, Alaska
    • Wrangell, Alaska
    • Cruise Wrangell Narrows, Alaska
    • Petersburg, Alaska
    • Cruise Inside Passage, Alaska
    • Cruise Tracy Arm Fjord, Alaska
    Sailing Dates:
    • June 2025
    • July 2025
    • August 2025
    • June 2026
    • July 2026
    • August 2026
    interior from
    Not Available
    oceanview from
    $8,275
    $828pernight
    balcony from
    $9,665
    $967pernight
    suite from
    $13,100
    $1,310pernight
    Rewards & Bonus Offers:
    • Up to $2,000 Visa Prepaid Card
    • Complimentary Dining, Cocktail Parties and More
     
    Was $10,665 – Save up to 9%
    Riverview from $8,275
    ($828pernight)
    4.9 rating out of 5  (7 reviews)
  • American Constellation
    4.9 rating out of 5  (7 reviews)

    14 Night Alaska Inside Passage

    American Constellation

    Departing from: Seattle, Washington
    Ports of Call:
    • Anacortes, Washington
    • Friday Harbor, San Juan Island, Washington
    • Cruise Queen Charlotte Sound, British Columbia
    • Cruise Inside Passage, Alaska
    • Ketchikan, Alaska
    • Wrangell, Alaska
    • Petersburg, Alaska
    • Cruise Tracy Arm Fjord, Alaska
    • Cruise Glacier Bay National Park
    • Haines, Alaska
    • Skagway, Alaska
    • Juneau, Alaska
    Sailing Dates:
    • May 2025
    • May 2026
    interior from
    Not Available
    oceanview from
    $10,200
    $729pernight
    balcony from
    $11,730
    $838pernight
    suite from
    $15,455
    $1,104pernight
    Rewards & Bonus Offers:
    • Up to $2,000 Visa Prepaid Card
    • Complimentary Dining, Cocktail Parties and More
     
    Riverview from $10,200
    ($729pernight)
    4.9 rating out of 5  (7 reviews)

Luxury American Cruise Lines Cruises

Our luxury cruise experts assist with every aspect of booking American Cruise Lines river cruises, including getting you the most value on your river cruise vacation. Sail away to some of the country's top river destinations, including luxury Mississippi River Cruises. We cater to customers who value exceptional service, product knowledge, and first-hand experience above all else. Receive complimentary onboard perks and unparalleled service when you book American Cruise Lines river cruise deals with LuxuryOnly Cruises.

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